A Biocompatible Cinchonine-Based Catalyst for the CO2 Valorization into Oxazolidin-2-ones Under Ambient Conditions
L. Invernizzi, C. Damiano, E. Gallo Chem. Eur. J. 2025, 0, e202500473 A metal-free, biocompatible catalyst for the cycloaddition of CO2 to N-alkyl aziridines was easily obtained by protonating the natural and nontoxic alkaloid (+)-cinchonine. This bifunctional catalytic system promoted the synthesis of the desired products under very mild experimental conditions (room temperature and atmospheric CO2 pressure) … Read more