Courses

Here is the link to the PhD courses enrollment online service.

For all the information regarding the Soft Skills courses for PhD students, click here.

For further information about the courses, please contact: alessandra.magenga@unimi.it

Academic year 2025/2026

ContentsLecturersRooms and Dates
Emerging Approaches to Natural Product Synthesis and Derivatization

Coordinator: Valerio Fasano

2 CFU

 
The aim of this corse is to explore and develop innovative strategies for the design, construction,
and modification of complex natural products. Particular emphasis will be placed on harnessing emerging technologies
such as photochemistry and electrochemistry to enable selective transformations and late-stage functionalizations that
expand the chemical space of bioactive molecules. By integrating modern concepts in asymmetric synthesis,
carbon–carbon bond formation, and retrosynthetic analysis with these novel approaches, the course seeks to establish efficient and versatile methodologies for accessing both natural scaffolds and their tailored derivatives. The course will
be delivered by instructors with deep expertise in total synthesis and state-of-the-art synthetic methodologies.

Mattia Silvi (a)
Bertuzzi Giulio (b)
Valerio Fasano (c)
(a)18/12/2025, 14.30-16.30, Aula Jommy
 
(a) 19/12/2025, 12.30-14.30, Aula Jommy

(b) 20/01/2026, 10.30-12.30 e 14.30-16.30, Aula Canonica

(c) 21/01/2026, 14.30-16.30, Aula Canonica

Machine Learning for accelerating discoveries in chemistry

Coordinator: Rocco Martinazzo

3 CFU


Learning objectives: Students will gain an understanding of key machine learning methods
and how these are applied to problems in chemistry,
including materials discovery, drug design and synthesis planning.

Artificial Intelligence & Machine Learning Monica Civera
This lecture introduces the core concepts of artificial intelligence (AI) and machine learning
(ML). It covers the key types of supervised, unsupervised, and reinforcement learning, the
perceptron model and the modern artificial neural network (ANN) architectures.

Traditional modeling in chemistry Davide Ceresoli
This lecture will present “atomistic modeling techniques” to study the structure,
properties, and dynamics of materials by explicitly considering the behavior of individual
atoms and their interactions. These techniques, which include Molecular Dynamics (MD)
and Monte Carlo (MC) simulations, use interatomic potentials (or force fields) derived from
quantum mechanics (i.e. Density Functional Theory) to describe the forces between atoms,
allowing for the simulation of systems ranging from
small molecules to large crystalline or
amorphous solids.

ML-based accelerated modeling: materials Davide Ceresoli
This lecture will introduce fundamental ML algorithms using chemical datasets, featuring
descriptors of chemical composition, crystal sites and structures, electronic band-
structure/DOS and spectroscopic properties of inorganic materials. This lecture will also
present two case studies of the prediction of materials properties and synthetizability of
halide perovskites and MOFs.

ML-based accelerated modeling: drug discovery Monica Civera
This lecture focuses on machine learning approaches that accelerate drug design. It will
explore how molecular representations (e.g., SMILES, molecular graphs, and embeddings)
are used to train ML models capable of generating novel compounds, predicting
bioactivity, and optimizing molecular properties. Specific examples will be also discussed.

Machine Learning in Physics and Chemistry Alexander Tkatchenko
This lecture will cover the huge advances (as well as many remaining challenges) of
applying (deep) machine learning methods for solving problems in physics and chemistry.
In particular, I will discuss different ways to combine prior domain knowledge with the high
flexibility of nonlinear ML methods. Specific examples will include applications of ML for
chemical discovery and for accelerating molecular simulations.

Chemical reactions in cheminformatics Gilles Marcou
This topic covers ML strategies and tools for predicting chemical reactions and designing
synthetic routes. Examples will be also discussed.

Exercises with SciFinder-n Luca Pignataro
This hands-on session introduces students to AI models for retrosynthetic analysis.
Participants will practice designing synthetic routes for target molecules (questa parte
dipende dalla possibilità di utilizzare un tool alternativo a Scifinder-n)
Civera Monica (a)
Davide Ceresoli (b)

Alexandre Tkatchenko (c)
Gilles Marcou (d)
Luca Pignataro (e)
(a) 16/02/2026, 8.30-10.30
Aula G15

(b) 16/02/2026,14.30-16.30
Aula G15

(a) 17/02/2026, 10.30-12.30
Aula G15

(b) 18/02/2026,10.30-12.30


(c) 19/02/2026, 10.30-12.30

(c) 20/02/2026, 10.30-12.30

(c) 23/02/2026, 10.30-12.30

(c) 24/02/2026, 10.30-12.30

(c) 25/02/2026, 10.30-12.30
Milestones in Chemistry: Nobel Prize-winning discoveries and their scientific impact

Coordinator: Valerio Fasano

2 CFU

 
This course offers an overview of groundbreaking research recognized by the Nobel
Committee, highlighting how these discoveries have shaped and transformed the field of
chemistry. Through detailed case studies, students will explore the scientific processes and
experimental approaches that led to each achievement, gaining insight into the creativity,
persistence, and innovation behind these landmark contributions. The course also
examines the effects of these discoveries across various branches of chemistry, illustrating
their pivotal role in advancing both theoretical understanding and practical applications.
Topics covered include discoveries of natural antimalarials or antibodies, as well as
inventions of polymers or Nobel Prizes for theoretical chemistry.


The course is mandatory for students enrolled in the PhD in chemistry.
Alberto Dal Corso (a)
Valerio Fasano (b)
Riccardo Conte (c)
Daniele Fiorito (d)
Diego Caprioglio (e)
(a)2/02/2026, 14.30-16.30, Aula Canonica
 
(b) 3/02/2026, 14.00-16.00, Aula Canonica
 
(c) 4/02/2026, 14.30-16.30, Aula Canonica
 
(d) 5/02/2026, 14.00-16.00, Aula Canonica
 
(e) 10/02/2026, 14.30-16.30, Aula Canonica
Journal Club

Coordinator: Anna Bernardi

3 CFU


Students will be asked to select two recent and relevant articles, in areas not fully
overlapping with their research topic, and to critically present them to the group. Each
presentation is followed by a discussion opened by a second student, with the role of
reviewer, and led by one of the teachers. The objectives are to provide participants with
the ability to read, interpret and contextualize the chemical literature, to improve their
presentation skills, to stimulate their active participation in chemical conversations. The
introductory part of the course (2h) aims to provide students with basic knowledge about
bibliometry and how it is currently used in the evaluation processes.


The course is mandatory for students enrolled in the PhD in chemistry.
Anna Bernardi (a)
Rocco Martinazzo (b)
Claudia Dragonetti (c)
04/02/2026, 10.30-12.30
Aula G30

18/03/2026, 14.00-17.00
Aula V7

19/03/2026, 14.00-17.00
Aula C21
Experimental Design and Data Planning and Analysis for Advanced Chemical Projects

Coordinator: Valentina Pifferi

2 CFU

 
This course allows the student to acquire specific knowledge regarding the principles of
quality management and control, in a quality-by-design approach. Experience will also be
gained in planning (through experimental design) experiments and analytical protocols for
different applications. The student will also be trained, through chemometric techniques,
in the discussion of the data on the basis of the statistical analysis of them. Moreover, at
the end of the course, the students will be able to use (in a basic way) some statistical
methods and softwares (Excel, JMP, CAT) for Quality Control, Experimental Design and
Chemometric techniques for Multivariate Analysis.


The course is mandatory for students enrolled in the PhD in chemistry.
Valentina Pifferi (a)
Falciola Luigi (b)
10/02/2026, 10.30-12.30,
aula Bianchi

11/02/2026, 14.00-16.00,
aula Bianchi

13/02/2026, 14.00-16.00,
aula Bianchi

16/02/2026, 10.30-12.30,
aula Bianchi

17/02/2026, 14.00-16.00,
aula Bianchi
Graphic communication of Scientific Research to make your presentation more incisive

Coordinator: Daniele Passarella

2 CFU

 
The course goal is to learn graphic language rukles and to master them. The main topic is
teaching the students how to make the correct graphic choices when they make
communication for scientific research.

 
The course is mandatory for students enrolled in the PhD in chemistry.
Serena Ghezzi
16/03/2026, 9.00-13.00
Aula 101

17/03/2026, 9.00 – 13.00
Aula 601

20/03/2026, 9.00 – 13.00
Aula Farina
Introduction to modelling of molecular materials

Coordinator: Leonardo Lo Presti

2 CFU

The course is designed for students who do not have a background in theoretical or
computational research. The aim of the course is to illustrate the fundamental principles
of computational simulation of molecular systems in various aggregation states, and in
particular which properties can be obtained using classical and quantum methods. The course
will consist of theoretical lectures and exercises in a computational laboratory.

Leonardo Lo Presti
Giovanni Macetti
27/04/2026, 14.30-16.30
Aula Bianchi

28/04/2026, 14.30-16.30
Aula Canonica

29/04/2026, 14.00-17.00
Aula Informatizzata 310

30/04/2026, 14.00-17.00
Aula Informatizzata 311
New trends in efficient and sustainable preparation of high-value chemicals

Coordinator: Lucia Tamborini, Alessandra Puglisi

2 CFU


In recent years, sustainability has become a key priority for research centers
and chemical industries, which are increasingly focused on developing environmentally
friendly and economically efficient processes. At the same time, companies face growing
pressure to maintain high quality standards, reduce costs, and accelerate production
timelines. In this context, adopting innovative chemical strategies that enhance process
sustainability—by minimizing or eliminating the use and generation of hazardous substances—is essential.
The course is organized into several thematic sessions, each dedicated to cutting-edge
enabling technologies applied to the synthesis of high-value compounds, including active
pharmaceutical ingredients and intermediates.
Its main goal is to provide participants with a solid understanding of emerging
technologies, equipping future chemists to tackle current synthetic challenges and
contribute to a safer and greener transformation of the chemical and pharmaceutical sectors.
This year’s edition will focus specifically on photochemistry and mechanochemistry,
offering in-depth insights into their principles and practical applications.


The course is mandatory for students enrolled in the PhD in chemistry.
Davide Ravelli (a)
Giancarlo Cravotto
(b)

(a) 07/05/2026,
9.30-12.30 + 14.30-16.30
Aula BS – Biologia

(b) 14/05/2026,
9.30-12.30 + 14.30-16.30
Aula 204
Metal catalyzed reactions leading to the formation of C-N bonds
 
Coordinator: Fabio Ragaini

2 CFU


To acquire up-to-date competences on transition metal-catalyzed reactions leading to
the formation of C-N bonds. To acquire knowledge about the mechanism of the involved
reactions, in the aim of better mastering the synthetic results.


Fabio Ragaini (a)
Docente straniero (b)
11/05/2026, 14.30-16.30
Aula Canonica

12/05/2026, 14.30-16.30
Aula Canonica

13/05/2026, 14.30-16.30
Aula Farina

28/05/2026, 14.30-16.30
Aula Farina

29/05/2026, 14.30-16.30
Aula Canonica
Applications of advanced NMR techniques

Coordinator: Francesca Vasile

2 CFU


The student will acquire skills on the analysis of the structure, the conformation and the
dynamic behaviour of molecules using NMR techniques and computational calculations.
During the course, NMR techniques useful to analyze the absolute configuration of
stereocenters, the mixtures and to study the interactions between molecules and their
biological target will be presented.
Francesca Vasile (a)
Guido Tiana (b)
Laura Ragona (c)
(a) 11/02/2026, 9.30-12.30,
aula Bianchi

(a) 12/02/2026, 9.30-12.30,
aula Bianchi

(c) 16/02/2026, 14.30-16.30,
aula Bianchi

(b) 24/02/2026, 14.30-16.30,
aula Montanari