Academic year 2024/2025
| Contents | Lecturers | Rooms and Dates |
| Journal Club Coordinator: Anna Bernardi 2 CFU The course is organized as a journal club: students will be asked to select two recent and relevant articles, in fields distinct from their research topic, and to critically present them to the group. Each presentation is followed by a discussion opened by a second student, with the role of reviewer, and led by one of the teachers. The objectives are to provide participants with the ability to read, interpret and contextualize the chemical literature, to improve their presentation skills, to stimulate their active participation in chemical conversations. The introductory part of the course (2h) aims to provide students with basic knowledge about bibliometry and how it is currently used in the evaluation processes. The course is mandatory for students enrolled to the course | Anna Bernardi (a) Rocco Martinazzo (b) Claudia Dragonetti (c) | Feb 2025 |
| Advances in natural products synthesis: from carbohydrates to drug conjugates Coordinator: Valerio Fasano 2 CFU This course examines recent advancements in the synthesis and application of natural products. The first section introduces modern strategies for synthesizing key classes of natural products. The second section delves into carbohydrate chemistry, a category of natural products commonly utilized in the design of complex molecules for therapeutic and industrial applications. The final section explores the integration of natural products in antibody-drug conjugates and PROTACs, offering a deeper understanding of their practical applications. The course will be taught by experts in (bio)organic chemistry. | Valerio Fasano Alberto Dal Corso Sarah Mazzotta Giuseppe D’Orazio Andrea Citarella | 03-06-2025 9:30 – 11:30 04-06-2025 9:30 – 11:30 05-06-2025 9:30 – 11:30 06-06-2025 14:30 – 16:30 |
Graphic communication of Scientific Research to make your presentation more incisive Coordinator: Daniele Passarella2 CFU The course goal is to learn graphic language rukles and to master them. The main topic is teaching the students how to make the correct graphic choices when they make communication for scientific research. The course is mandatory for students enrolled to the course. | Serena Ghezzi | March 2025 |
| Instrumental methods for the analysis of materials and surfaces: molecular spectroscopy, optical microscopy, X-ray-based techniques and electron microscopy Coordinator: Vittoria Guglielmi 2 CFU Use of unconventional analytical techniques, not included in the Bachelor’s and Master’s degree courses in chemistry. The course is mandatory for students enrolled to the course. | Vittoria Guglielmi | May 2025 |
| Chiral Iron Complexes in Asymmetric Catalysis Coordinator: Emma Gallo 2 CFU The course aims to train students on the design, characterization and the application of chiral iron complexes in asymmetric catalysis. From a green chemistry perspective, developing new synthetic methods using iron, which is abundant, inexpensive, environmentally benign, and relatively nontoxic in comparison with other metals, is a major advantage. The ability to use iron in homogeneous asymmetric catalysis is promising for the development of greener synthetic methods. In this course, the iron Lewis acids will be sorted according to the type of structure of the ligand (chiral oxazoline ligands, chiral Schiff ligands, chiral salen/salan ligands, chiral bipyridines, …). The synthesis of selected ligands will be presented. The mechanism of the reactions will be discussed in some chemical reactions. Particular emphasis will be put on useful synthetic transformations. Special attention will be given to examples from the recent literature. | Ollevier Thierry | 26-11-2024 14:30 – 16:30 (V5) 27-11-2024 14:30 – 16:30 (V5) 3-12-2024 14:30 – 16:30 (V5) 4-12-2024 14:30 – 16:30 (V5) 10-12-2024 14:30 – 16:30 (V5) |
| Introduction to modelling of molecular materials Coordinator: Leonardo Lo Presti 2 CFU The course is designed for students who do not have a background in theoretical or computational research. The aim of the course is to illustrate the fundamental principles of computational simulation of molecular systems in various aggregation states, and in particular which properties can be obtained using classical and quantum methods. The course will consist of theoretical lectures and exercises in a computational laboratory. | Leonardo Lo Presti Giovanni Macetti | April 2025 |
| Experimental Design and Data Planning and Analysis for Advanced Chemical Projects Coordinator: Valentina Pifferi 2 CFU This course allows the student to acquire specific knowledge regarding the principles of quality management and control, in a quality-by-design approach. Experience will also be gained in planning (through experimental design) experiments and analytical protocols for different applications. The student will also be trained, through chemometric techniques, in the discussion of the data on the basis of the statistical analysis of them. Moreover, at the end of the course, the students will be able to use (in a basic way) some statistical methods and softwares (Excel, JMP, CAT) for Quality Control, Experimental Design and Chemometric techniques for Multivariate Analysis. | Valentina Pifferi (a) Falciola Luigi (b) External professor to be determined (c) | February 2025 |
| New trends in efficient and sustainable preparation of high-value chemicals Coordinator: Lucia Tamborini, Alessandra Puglisi 2 CFU In recent years, research centers and companies are paying increasing attention to the development of more economically and environmentally sustainable chemical processes. While global climate change calls for the development of more efficient and greener manufacturing processes, pressure on pharmaceutical and fine chemical production is increasing due to rising quality standards, time constraints, and need for cost effectiveness. Therefore, novel approaches are required to improve the sustainability of the current synthetic practices and to avoid or reduce the use or generation of hazardous substances in the design of chemical products or processes. The course will be divided in different sessions and will present and discuss innovative enabling technologies, such as flow chemistry and catalysis (e.g., biocatalysis, photocatalysis), for the obtainment of high value chemicals, i.e., active pharmaceutical ingredients (APIs) or their intermediates. The objective of the course is to introduce students to emerging enabling technologies to overcome today’s synthetic challenges, making the chemical and pharmaceutical sectors greener and safer. | Gianvito Vilè | April 2025 |
| Innovative aspects in the chemistry of ligands for transition metals: synthesis, properties and use in catalysis Coordinator: Fabio Ragaini 2 CFU To acquire up-to-date competences on metal-ligand interactions and on how to take advantage of them. | Fabio Ragaini (a) To be determined (b) | April 2025 |
| Applications of advanced NMR techniques Coordinator: Francesca Vasile 2 CFU The student will acquire skills on the analysis of the structure, the conformation and the dynamic behaviour of molecules using NMR techniques and computational calculations. During the course, NMR techniques useful to analyze the absolute configuration od stereocenters, the mixtures and to study the interactions between molecules and their biological target will be presented. | Francesca Vasile (a) Guido Tiana (b) Laura Ragona (c) | February 2025 |
| HPC@Unimi: Indaco for molecules and solids Coordinator: Rocco Martinazzo 3 CFU Fundamentals of computers and networks, UNIX; installation and configuration of programs to access Indaco; software optimization and management. The electronic problem, introduction and definition. Chemical bond and electronic properties; molecular structure and transformations. Methods for solid state physics; application to periodic and non-periodic systems. | Alessio Alessi (a) Michele Bensi (b) Rocco Martinazzo (c) Guido Fratesi (d) | June 2025 |